CD8A and infection: Combining these data, a model can be drawn where a so far undefined population/s of non-hematopoietic cells that get infected already at the first round of infection will become a major reservoir of latent CMV, and will occasionally process and present a limited and defined set of CMV-derived antigens to memory CD8 T cells, causing their accumulation or/and maintenance in the periphery (Figure 1C).