High expression of miR-103 and miR-107 (miR-103/107) was found in the presence of hypoxia, thereby potentiating metastasis suppressors death-associated protein kinase (DAPK) and Krüppel-like factor 4 (KLF4) downregulation and hypoxia-induced motility and invasiveness of colorectal cancer cell lines [34]. The gene discussed is KLF4; the disease is colorectal cancer.