Meschia et al.[4] found no association of ALOX5AP variants and ischemic stroke in a US population, Zhang et al.[5] reported the ALOX5AP variant SG13S114T/A was associated with increased risk of stroke in Chinese males, and Linsel-Nitschke et al.[20] found HapB was associated with an increased risk of myocardial infarction in a German population. Here, ALOX5AP is linked to stroke disorder.