ANXA5 and neoplasm: Since DCs and macrophages partly utilize different clearance mechanisms (Hoves et al., 2011), one possibility to enable enhanced access of DCs to RT-induced apoptotic and necrotic tumor cells is to block their clearance by macrophages with the PS-binding protein AnnexinA5 (AnxA5; Bondanza et al., 2004; Frey et al., 2009).