As shown in Table 3, the associations of rs2274700 (A473A) with DBP (P = 2.1×10−3) and SBP (8×10−5), and hypertension risk (7.9×10−3)were significant only in individuals with low CRP levels (<2.0 mg/l), but not in those with elevated CRP levels (≥2.0 mg/l) (P≥0.0807, P for interaction: 0.001–0.047). The gene discussed is CRP; the disease is Hypertension.