Overall, KRAS mutations were observed in 36.30% (95% confidence interval (CI) 26.57%-46.92%) of polypoid adenomas and 27.85% (95% CI 19.58%-37.39%) of flat adenomas (Figure 2, Table S2C), resulting in no statistically significant difference (p = 0.2, odds ratio 0.67 (95% CI 0.37%-1.24%)). Here, KRAS is linked to adenoma.