Using the ELISA we tested the hypotheses that Adv36 was present within the Swedish population living in the area of the capital Stockholm, that Adv36 was associated with obesity in children and adults in Stockholm area, that Adv36 was associated with lower blood lipid levels, and that Adv36 was associated with insulin sensitivity in non-diabetic individuals. Here, INS is linked to obesity due to melanocortin 4 receptor deficiency.