Taken together, these results suggest that the t(11;14) genotype and high CCND1 expression are associated with resistance to 8-NH2-Ado/8-Cl-Ado in the context of myeloma while the discrepancies between cyclin D1 transcript and protein abundances noted above suggest that this association is not meaningful in the context of mantle cell lymphoma. Here, CCND1 is linked to plasma cell myeloma.