By contrast, individuals with biopsy-proven FSGS, IgA nephropathy and MN had a significant increase in RANK expression (FSGS 0.42±0.07, IgA nephropathy 0.37±0.10, MN 0.67±0.24, versus control 0.24±0.04, p < 0.01) (Figure 2B). Here, TNFRSF11A is linked to IgA glomerulonephritis.