TNFSF11 and focal segmental glomerulosclerosis: By contrast, individuals with FSGS, IgA nephropathy and MN had a moderate increase in RANKL expression (FSGS 0.25±0.07, IgA nephropathy 0.22±0.08, MN 0.27±0.08, versus control 0.11±0.05, p < 0.01) (Figure 2C).