Epicutaneous (EC) immunization of mice with Ova allergen promotes IL-17 expression in the skin and drives the generation of IL-17 producing T cells in the inguinal, axillary and cervical lymph nodes (DLNs) and spleen and a local and systemic Th17 response associated with neutrophilic airway inflammation [34], [35]. The gene discussed is IL17A; the disease is inflammatory response.