The reported risk factors of BM in NSCLC include histology, [12,14-16,21,24] extent of disease,[10,13,22] adjuvant/neoadjuvant therapy, [12-15,22] younger age, [8,10,23] incomplete resection,[13]and carcinoembryonic antigen serum level[32]. This evidence concerns the gene CEACAM5 and non-small cell lung carcinoma.