To see whether MSC-derived Gal-1 enhanced tumor growth by contributing to establishment of tumor immuno-privilege similarly to tumor-cell derived Gal-1 did [18], [19], B16F10 melanoma cells were co-injected with wtMSCs or MSCGal-1−/− into X-SCID immuno-compromised mice. This evidence concerns the gene LGALS1 and melanoma.