TBX3 and breast carcinoma: To rule out the possibility that TBX3, which is primarily overexpressed in luminal E-cadherin-positive breast cancer lines and estrogen receptor-positive breast tumors [77], [78], contributed to the pro-invasive effects elicited by TBX2, we investigated TBX3 expression in our TBX2-dependent breast epithelial model systems (Figure S5).