Of note, both primary and recurrent tumor shared identical mutations affecting exon 5 of TP53 and the R132H mutation in IDH1. The persistence of both the TP53- mutation affecting exon 5 and the IDH1- mutation together with the introduction of a partial LOH1p in the recurrent tumor strongly argue for the analysis of tumor tissue in both the analyses of the primary and the recurrent tumor. The gene discussed is TP53; the disease is neoplasm.