In addition, the levels of TLR4 (F(1,23) = 6.5066, p<0.05; Fig. 4A), COX1 (F(1,23) = 1.5703, p<0.05; Fig. 4B), COX2 (F(1,23) = 33.3854, p<0.001; Fig. 4C), NF-κB (F(1,23) = 23.8678, p<0.001; Fig. 4D), CD45 (F(1,23) = 20.11113, p<0.001; Fig. 4E), and iNOS (F(1,23) = 6.8425, p<0.05; Fig. 4F) were significantly increased after the onset of hyperglycemia. This evidence concerns the gene TLR4 and Hyperglycemia.