FN1 and diabetic kidney disease: According to the results of histopathological evaluation, although diabetic nephropathy rats showed a 2.2-fold increase in the glomerular area, mild but significant increases in diffuse and exudative lesions, and a slight increase in the mesangial matrix, (−)-epigallocatechin 3-O-gallate could affect glomerular hypertrophy and these lesions at 50 and 100 mg doses, reflecting the effects of AGEs, TGF-β1, and fibronectin levels (Figures 8 and 10).