CA2 and autoimmune pancreatitis: Significant homology between human CA-II and alpha CA of Helicobacter pylori (H. pylori) has been noted [66], and reactivity against a pancreatic homologue of Helicobacter has been demonstrated [54], suggesting that H. pylori infection may be involved in triggering AIP and AIP-related sclerosing cholangitis via mechanisms, such as, molecular mimicry, in individuals with a genetic predisposition [54, 66].