Other activated genes included transcriptional cofactor pirin, an iron-binding nuclear protein involved in apoptosis [73]; two members of the amino acid/polyamine transport system, SLC12A8A [74] and SLC7A11 [75]; KIT ligand, the ligand of the tyrosine-kinase receptor encoded by the KIT locus, implicated in pigmentation [76] and cancer [77]; α-arrestin 4 [78]; transmembrane protein TMEM158; FAM70A and putative protein ENSG00000204134. Here, TMEM158 is linked to cancer.