We also found that expression of SRSF1 and PRMT1 in the Nalm-6 (TEL-AML1 positive) and Reh (TEL-AML1 negative) cell lines could be attenuated with chemotherapy drugs; additionally, SRSF1 and PRMT1 were associated with each other in leukemia cells in vivo. Here, RUNX1 is linked to leukemia.