When we analyzed the CDCA3 protein expression in primary OSCCs and paired normal oral tissues from 95 patients and oral premalignant lesions (OPLs) from 20 patients using the immunohistochemistry (IHC) scoring system, the CDCA3 IHC scores in the primary OSCCs, OPLs, and normal oral tissues ranged from 2.5 to 225.0 (median, 95.0), 2.5 to 50.0 (median, 15.0), and 2.5 to 87.5 (median, 22.5), respectively. The gene discussed is CDCA3; the disease is dysplastic oral keratinocyte.