Anand et al. concluded from their study that CRP was independently associated with CAD in Asian Indians after adjustment for Framingham risk factors and anthropometric measurements.40 The INTERHEART study demonstrated that increased apolipoprotein B/apolipoprotein AI, smoking, abdominal obesity, psychosocial stress, diabetes mellitus and hypertension accounted for 90% of the CAD risk in Asian Indians.41 This evidence concerns the gene APOB and hypertensive disorder.