PLK4 and hepatocellular carcinoma: Results suggested that PLK4 was also an independent predictor for overall survival (HR: 0.556, 95% CI: 0.376−0.822, P = 0.003) and disease-free survival (HR: 0.547, 95% CI: 0.382−0.783, P = 0.001) of HCC patients (Table 3).