No association between rs2377422 and the subsets of RA was found in the three Malaysian sample sets when analyzed separately (shown in Table 2) or in the meta-analysis for ACPA-negative RA within these sample sets (allele model: ORoverall = 0.88, 95% CI 0.71–1.10; Phet = 0.94, I2 = 0%, data not shown). Here, PRTN3 is linked to rheumatoid arthritis.