Furthermore, miR-25 has been found to be expressed in several malignant cell lines (ovarian cancer cell line and cholangiocarcinoma), where it is involved in regulation of apoptosis and cell proliferation by targeting proapoptotic proteins as Bim and Trail (TNF-related apoptosis inducing ligand) [17, 28]. Here, TNFSF10 is linked to cholangiocarcinoma.