The resulting subnetwork included 457 edges and 101 GBM-related genes, which accounted for 57.38% of GBM-related genes (176) in the GBM-specific miRNA-TF mediated regulatory network and were regulated by only 26 GBM-related miRNAs (24.24%) and 24 TFs (16.90%). This evidence concerns the gene TF and glioblastoma.