Pulchellin treatment (group P) promoted an enhancement of adhesion (CD54) and costimulatory (CD80) molecules expression in peritoneal macrophages (p < 0.01), a significant reduction in the number of CD4+CD25+ Treg cells (p < 0.01) and non-significant reduction in the number of CD8 cells and dendritic cells (p > 0.05) relative to the tumor control group (T group) (Table 1). The gene discussed is CD4; the disease is neoplasm.