Notably, we found also a significant direct relationship of c-β-catenin expression with c-menin expression and, following the immunohistochemical criteria suggested by Pelosi et al(13) who defined the immunostaining pattern of tumor cells for β-catenin and E-cadherin as arrayed or disarrayed, we searched for possible correlations between these patterns of immunostaining with the other markers analyzed. This evidence concerns the gene CDH1 and neoplasm.