INS and diabetes mellitus: Four out of ten participants were male and at baseline the pooled average age was 60 years (SD 9.5), BMI 31.5 (SD 5.6), diabetes duration was 8.1 years (SD 7.0), HbA1c level 8.23% (SD 1.80), and 81.9% used insulin and/or oral glucose lowering agents.