MSH6 and renal cell carcinoma: By examining immunostaining patterns of several protein candidates coded by these genes, we were able to assign tumors with high MVD as well as DEK and MSH6 positivity to group A, high or low MVD and MSH6 negative tumors to group B, and tumors with low MVD but DEK and MSH6 positivity to group C. Examples of immunostained RCC are shown inAdditional file 11: Figure S4.