Of the more highly expressed genes in CF18ac, the highest fold-change (4.90) was observed for AK235118 (a porcine EST) which belongs to the systemic lupus erythematosus pathway, while interleukin 8 (IL8) was the most highly expressed genes in CF4ab with a fold-change of 4.93. The gene discussed is CXCL8; the disease is systemic lupus erythematosus.