Additionally, IL-10 mRNA level was significantly lower in the intestinal mucosa of PI-IBS patients (0.15 ± 0.02) than in non-PI-IBS patients (0.28 ± 0.02) or healthy people (0.30 ± 0.02) (both P < 0.05), but there was no significant differences between the non-PI-IBS and control groups (P > 0.05; Figure 1). The gene discussed is IL10; the disease is irritable bowel syndrome.