FOLH1 and retinal disorder: Finally, to determine the therapeutic potential of PSMA as a target in retinopathies, we treated wild type mice undergoing OIR with the small molecule PSMA inhibitor 2-PMPA in two dosing protocols, systemic administration of 100mg/kg 2-PMPA either once on P14 or daily from P14-P16 (Figures 7 A, B).