Recently, chemokines (CCL2, CCL5 and CX3CL1) and chemokine receptors (CCR2, CCR5 and CX3CR1) have been strongly implicated to play critical roles in mediating inflammation, macrophage recruitment and atherosclerosis progression by multiple lines of evidence, including expression, functional and epidemiologic data [8]–[20]. This evidence concerns the gene CCR2 and atherosclerosis.