Despite the marked improvement in allergic airways responses observed when blood adiponectin is elevated by exogenous administration [17] or when blood adiponectin was elevated endogenously consequent to T-cad deficiency (Figures 1, 3, 4, 5), we observed little impact of adiponectin deficiency alone on allergic airways responses (Figure 6). The gene discussed is CDH13; the disease is hyperinsulinemic hypoglycemia, familial, 4.