Infection with CVB3 induced a slight increase of CD4+ T cells (23±0.15% of MNCs, p = 0.04 vs. PBS-Co) in the spleen of untreated mice, which was however further potentiated by MSCs (38±4.8% of MNCs, p = 0.016 vs. PBS-CVB3). The gene discussed is CD4; the disease is infection.