Parasitemias of the cultures kept at 0.5 μM and 1.0 μM Shld-1 were reduced by 11% and 18% after the first reinvasion cycle (48 hours) and by 25% and 45% after the second cycle, respectively, compared to no Shld-1 controls (Fig. 1). The gene discussed is SHLD1; the disease is parasitic infectious disease.