Binding predictions for Ag85B-TB10.4, Ag85B-ESAT-6, and Mtb72f were generated for 89 Class I HLA alleles representing the three most common alleles of each of the three Class I genes – HLA–A, HLA–B, and HLA–C – in populations with a high burden of TB identified by the World Health Organization (WHO) [24]. This evidence concerns the gene HLA-B and tuberculosis.