TP53 and lung cancer: In lung cancer cells, induction of miR-34 results in apoptosis[36, 37] and miRNA profiling shows that the expression of miR-34a, miR-34b, and miR-34c are directly correlated with expression of the p53 tumor suppressor[38], suggesting that miR-34 is involved in regulating apoptosis as a regulatory target of p53.