ESR1 and neoplasm: Of the clinical-pathological variables (age, size, LN, and tumor grade) and biomarkers (ER, PR, HER2, EGFR, TN status, VEGF-R1, and VEGF-R2) analyzed, tumor stromal VEGF-A expression levels were strongly correlated only with both epithelial and tumor stromal VEGF-R1 levels (P = 0.03 for both).