The observations by Antalis et al. that triple negative breast cancer cell lines (i.e., lacking ER, progesterone receptor, and ERBB2), namely, MDA-MB-231 and MDA-MB-436, had many more lipids droplets as compared to the ER+ MCF-7 cell line leads to the investigation of neutral lipid composition and metabolism in these cells [75]. This evidence concerns the gene ESR1 and triple-negative breast carcinoma.