EZH2 has been detected in tumors with various origins, such as urothelial carcinoma, squamous cell carcinoma of the esophagus, gastric cancer, glioma, renal cell carcinoma, non-small cell lung carcinoma (NSCLC), colorectal carcinoma and breast cancer [14-21]. The gene discussed is EZH2; the disease is non-small cell lung carcinoma.