The results of multivariate Cox regression analysis showed that Aurora Kinase A was an independent risk marker of overall survival(HR=11.263, 95%CI: 2.317–54.748, P=0.003) (Table 5), However, there was no significant relationship between Aurora Kinase B and the survival time of the patients with chondrosarcoma (p>0.05). This evidence concerns the gene AURKA and chondrosarcoma.