The ratio of positive expression of Aurora Kinase B protein in common chondrosarcoma groupIandII-III was 33.3% and 100% respectively (p<0.01); which means the more malignant tumor, the higher expression of the Aurora Kinase B. The ratio of positive expression was 85% and 57.7% in the recurrence group and non-recurrence group, respectively (p<0.05). The gene discussed is AURKB; the disease is cancer.