ACSL4 and neoplasm: The tumor from MCF-7 Tet-Off empty vector cells presented areas of hyaline strome with few tumor cells and few glands and was classified as a differentiated tumor (Figure 3 C).The MCF-7 Tet-Off/ACSL4 tumor xenografts treated with doxycycline also presented areas oh hyaline strome with few tumor cells and was classified as differentiated tumor (Figure 3 D).