Wild-type traditional serrated adenomas had a significantly higher mucosal Abi1 expression score compared to healthy mucosa, wild-type and BRAF-mutated HPP, but not to inflamed mucosa and to KRAS-mutated HPP (Table 2, 5.0±1.15; p<0.01 and p>0.1, respectively; Fig. 1E and I, Fig. 2). Here, ABI1 is linked to adenoma.