Interestingly, our work group recently identified the heterogeneous nuclear ribonucleoprotein K (hnRNP K) as one protein interaction partner of Abi1, while overexpression and aberrant localization of hnRNP K in tumor cells has previously been described to be correlated with adverse outcome in colorectal carcinoma patients [16], [17]. This evidence concerns the gene ABI1 and colorectal carcinoma.