FANCB and infection: We observed that pre-incubation of GFP-expressing trypomastigotes with anti-TcCRT IgG Fab significantly decreases cellular infection of WT MEF as evidenced by the decrease in the relative fluorescence units (RFU) of transgenic parasites in WT MEF (200±18) RFU after 72 hours when compared to parasites pre-incubated with an isotype control Fab antibody (760±30) RFU (Figure 4A).