Significance level increased in a multivariate model, after adjustment for HCV genotype, age, sex, baseline viral load, BMI, ALT, diabetes, and IL28B rs12979860 genotype (P = 0.06, OR = 1.33, CI = 0.988–1.796, Table 3) or when comparing rs10877012 CC carriers to AA carriers (P = 0.04). This evidence concerns the gene GPT and diabetes mellitus.