However, in multivariate models adjusted for other predictors of treatment outcome (age, sex, IL28B rs12979860 genotype, HCV genotype, HCV RNA levels, presence of diabetes, BMI, and liver fibrosis), 25(OH)D3 serum levels were clearly not associated with treatment outcome (p = 0.9 for 25[OH]D3≥20 ng/mL). Here, IFNL3 is linked to Hepatic fibrosis.