Humans KCNJ10 mutations are also associated to seizure susceptibility, idiopathic generalized epilepsy (Buono et al., 2004; Lenzen et al., 2005) or to complex syndromes that encompass epilepsy (Bockenhauer et al., 2009; Scholl et al., 2009; Reichold et al., 2010). This evidence concerns the gene KCNJ10 and epilepsy.