Thus, despite comparable infiltration of macrophages and DCs between infected Slamf1−/− mice Slamf1−/−, the number of infective amastigotes that are carried into the heart by infected migrating Slamf1−/− monocytes, DCs or macrophages will be greatly reduced and might be one of the contributing factors to the survival of Slamf1−/− mice to infection with the parasite. This evidence concerns the gene SLAMF1 and infection.