Evidence is mounting that strongly implicates an important role for Lyn in several types of leukaemia and lymphoma, especially chronic myeloid leukaemia (CML) [76], acute myeloid leukaemia (AML) [75,78], chronic lymphocytic leukaemia (CLL) [79], B-cell acute lymphoblastic leukaemia (B-ALL) [74], B-cell chronic lymphocytic leukaemia (B-CLL) [79], and B-Non Hodgkin’s lymphomas (B-NHL) [80]. Here, LYN is linked to chronic myelogenous leukemia, BCR-ABL1 positive.