First Widimsky, and then other authors, similarly found primary aldosteronism patients to be insulin resistant;141,142,145 on the other hand, they found no differences between patients with either primary aldosteronism or essential hypertension with regard to the prevalence of impaired glucose tolerance or diabetes.146 The study by Catena et al.142 produced findings different from those cited above in several ways. The gene discussed is INS; the disease is hypertensive disorder.